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Improvement of epidermal covering on AEC patients with severe skin erosions by PRIMA-1(MET)/APR-246
P63 is a major transcription factor regulating skin development and homeostasis. It controls many genes involved in cell proliferation, adhesion, and early differentiation. P63 is mutated in several rare syndromes called p63-related ectodermal dysplasia syndromes (ED). The main forms are EEC and AEC...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965199/ https://www.ncbi.nlm.nih.gov/pubmed/31949132 http://dx.doi.org/10.1038/s41419-020-2223-8 |