Accumulation of tissue factor in endothelial cells promotes cellular apoptosis through over-activation of Src1 and involves β1-integrin signalling

Accumulation of tissue factor (TF) within cells leads to cellular apoptosis mediated through p38 and p53 pathways. In this study, the involvement of Src1 in the induction of TF-mediated cell apoptosis, and the mechanisms of Src1 activation were investigated. Human coronary artery endothelial cell (H...

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Detalles Bibliográficos
Autores principales: Ethaeb, Ali M., Mohammad, Mohammad A., Madkhali, Yahya, Featherby, Sophie, Maraveyas, Anthony, Greenman, John, Ettelaie, Camille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965344/
https://www.ncbi.nlm.nih.gov/pubmed/31654241
http://dx.doi.org/10.1007/s10495-019-01576-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965344/
https://www.ncbi.nlm.nih.gov/pubmed/31654241
http://dx.doi.org/10.1007/s10495-019-01576-2

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