CXCR1 Expression to Improve Anti-Cancer Efficacy of Intravenously Injected CAR-NK Cells in Mice with Peritoneal Xenografts

One reason underlying the failure of current chimeric antigen receptor (CAR) immune therapy to treat solid tumors adequately is insufficient tumor infiltration of CAR immune cells. To address the issue, we electroporated natural killer (NK) cells with two mRNA constructs encoding the chemokine recep...

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Detalles Bibliográficos
Autores principales: Ng, Yu Yang, Tay, Johan C.K., Wang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965500/
https://www.ncbi.nlm.nih.gov/pubmed/31970285
http://dx.doi.org/10.1016/j.omto.2019.12.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965500/
https://www.ncbi.nlm.nih.gov/pubmed/31970285
http://dx.doi.org/10.1016/j.omto.2019.12.006

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