Tunable light and drug induced depletion of target proteins

Biological processes in development and disease are controlled by the abundance, localization and modification of cellular proteins. We have developed versatile tools based on recombinant E3 ubiquitin ligases that are controlled by light or drug induced heterodimerization for nanobody or DARPin targ...

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Detalles Bibliográficos
Autores principales: Deng, Wen, Bates, Jack A., Wei, Hai, Bartoschek, Michael D., Conradt, Barbara, Leonhardt, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965615/
https://www.ncbi.nlm.nih.gov/pubmed/31949141
http://dx.doi.org/10.1038/s41467-019-14160-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965615/
https://www.ncbi.nlm.nih.gov/pubmed/31949141
http://dx.doi.org/10.1038/s41467-019-14160-8

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