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Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis

Excessive mitochondrial fission acts as a pro-proliferative marker in some cancers and organ fibrosis; its potential role in renal fibroblast activation and fibrogenesis has never been investigated. Here, we showed more pronounced fragmented mitochondria in fibrotic than in non-fibrotic renal fibrob...

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Detalles Bibliográficos
Autores principales: Wang, Yating, Lu, Miaoqing, Xiong, Liping, Fan, Jinjin, Zhou, Yi, Li, Huiyan, Peng, Xuan, Zhong, Zhong, Wang, Yihan, Huang, Fengxian, Chen, Wei, Yu, Xueqing, Mao, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965618/
https://www.ncbi.nlm.nih.gov/pubmed/31949126
http://dx.doi.org/10.1038/s41419-019-2218-5