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Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis
Excessive mitochondrial fission acts as a pro-proliferative marker in some cancers and organ fibrosis; its potential role in renal fibroblast activation and fibrogenesis has never been investigated. Here, we showed more pronounced fragmented mitochondria in fibrotic than in non-fibrotic renal fibrob...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965618/ https://www.ncbi.nlm.nih.gov/pubmed/31949126 http://dx.doi.org/10.1038/s41419-019-2218-5 |