Endogenous and artificial miRNAs explore a rich variety of conformations: a potential relationship between secondary structure and biological functionality

Mature microRNAs are short non-coding RNA sequences which upon incorporation into the RISC ribonucleoprotein complex, play a crucial role in regulation of gene expression. However, miRNAs can exist within the cell also as free molecules fulfilling their biological activity. Therefore, it is emerging...

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Detalles Bibliográficos
Autores principales: Gangemi, C. M. A., Alaimo, S., Pulvirenti, A., García-Viñuales, Sara, Milardi, D., Falanga, A. P., Fragalà, M. E., Oliviero, G., Piccialli, G., Borbone, N., Ferro, A., D’Urso, A., Croce, C. M., Purrello, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965629/
https://www.ncbi.nlm.nih.gov/pubmed/31949213
http://dx.doi.org/10.1038/s41598-019-57289-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965629/
https://www.ncbi.nlm.nih.gov/pubmed/31949213
http://dx.doi.org/10.1038/s41598-019-57289-8

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