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Positive Allosteric Modulation of Alpha7 Nicotinic Acetylcholine Receptors Transiently Improves Memory but Aggravates Inflammation in LPS-Treated Mice

Neuroinflammation accompanies or even precedes the development of cognitive changes in many brain pathologies, including Alzheimer’s disease. Therefore, dampening inflammatory reactions within the brain is a promising strategy for supporting cognitive functions in elderly people and for preventing t...

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Detalles Bibliográficos
Autores principales: Lykhmus, Olena, Kalashnyk, Olena, Uspenska, Kateryna, Skok, Maryna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966166/
https://www.ncbi.nlm.nih.gov/pubmed/31998114
http://dx.doi.org/10.3389/fnagi.2019.00359