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α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome

Mechanism by which α-synuclein affects the progression of Parkinson's disease through Pyrin Domain Containing Protein 3 (NLRP3) was explored. Peripheral blood plasma of 40 Parkinson's disease patients and 40 normal healthy people attending the department of neurology of the Third Affiliate...

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Detalles Bibliográficos
Autores principales: Wang, Xiaohong, Chi, Jinghong, Huang, Di, Ding, Li, Zhao, Xiaojing, Jiang, Lai, Yu, Yang, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966172/
https://www.ncbi.nlm.nih.gov/pubmed/32010254
http://dx.doi.org/10.3892/etm.2019.8297