Cargando…
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome
Mechanism by which α-synuclein affects the progression of Parkinson's disease through Pyrin Domain Containing Protein 3 (NLRP3) was explored. Peripheral blood plasma of 40 Parkinson's disease patients and 40 normal healthy people attending the department of neurology of the Third Affiliate...
Autores principales: | Wang, Xiaohong, Chi, Jinghong, Huang, Di, Ding, Li, Zhao, Xiaojing, Jiang, Lai, Yu, Yang, Gao, Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966172/ https://www.ncbi.nlm.nih.gov/pubmed/32010254 http://dx.doi.org/10.3892/etm.2019.8297 |
Ejemplares similares
-
Systemic activation of NLRP3 inflammasome and plasma α-synuclein levels are correlated with motor severity and progression in Parkinson’s disease
por: Fan, Zheng, et al.
Publicado: (2020) -
Targeting Microglial α-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson’s Disease
por: Li, Yunna, et al.
Publicado: (2021) -
BAG3 promotes autophagy and suppresses NLRP3 inflammasome activation in Parkinson’s disease
por: Ying, Zhong-Ming, et al.
Publicado: (2022) -
Regulation of α-synuclein homeostasis and inflammasome activation by microglial autophagy
por: Choi, Insup, et al.
Publicado: (2022) -
Interaction between autophagy and the NLRP3 inflammasome in Alzheimer’s and Parkinson’s disease
por: Lu, Ranran, et al.
Publicado: (2022)