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Blood-Brain Barrier and Delivery of Protein and Gene Therapeutics to Brain
Alzheimer’s disease (AD) and treatment of the brain in aging require the development of new biologic drugs, such as recombinant proteins or gene therapies. Biologics are large molecule therapeutics that do not cross the blood-brain barrier (BBB). BBB drug delivery is the limiting factor in the futur...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966240/ https://www.ncbi.nlm.nih.gov/pubmed/31998120 http://dx.doi.org/10.3389/fnagi.2019.00373 |