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Cocaine Self-administration and Extinction Inversely Alter Neuron to Glia Exosomal Dynamics in the Nucleus Accumbens

Alteration of glutamatergic synaptic plasticity in the Nucleus Accumbens (NAc) has been implicated in cocaine-seeking behaviors. Astroglial mechanisms for maintaining extracellular glutamate homeostasis through cysteine/glutamate exchanger (xCT) and glutamate transporter GLT1 are dysregulated follow...

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Detalles Bibliográficos
Autores principales: Jarvis, Rachel, Tamashiro-Orrego, Alessandra, Promes, Vanessa, Tu, Leona, Shi, Jinyuan, Yang, Yongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966328/
https://www.ncbi.nlm.nih.gov/pubmed/31998080
http://dx.doi.org/10.3389/fncel.2019.00581