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Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation

Purpose: Tumor markers that are related to hypoxia, proliferation, DNA damage repair and stem cell-ness, have a prognostic value in advanced stage HNSCC patients when assessed individually. Here we aimed to evaluate and validate this in a multifactorial context and assess interrelation and the combi...

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Detalles Bibliográficos
Autores principales: van der Heijden, Martijn, Essers, Paul B. M., de Jong, Monique C., de Roest, Reinout H., Sanduleanu, Sebastian, Verhagen, Caroline V. M., Hamming-Vrieze, Olga, Hoebers, Frank, Lambin, Philippe, Bartelink, Harry, Leemans, C. René, Verheij, Marcel, Brakenhoff, Ruud H., van den Brekel, Michiel W. M., Vens, Conchita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966332/
https://www.ncbi.nlm.nih.gov/pubmed/31998639
http://dx.doi.org/10.3389/fonc.2019.01470