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Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation
Purpose: Tumor markers that are related to hypoxia, proliferation, DNA damage repair and stem cell-ness, have a prognostic value in advanced stage HNSCC patients when assessed individually. Here we aimed to evaluate and validate this in a multifactorial context and assess interrelation and the combi...
Autores principales: | van der Heijden, Martijn, Essers, Paul B. M., de Jong, Monique C., de Roest, Reinout H., Sanduleanu, Sebastian, Verhagen, Caroline V. M., Hamming-Vrieze, Olga, Hoebers, Frank, Lambin, Philippe, Bartelink, Harry, Leemans, C. René, Verheij, Marcel, Brakenhoff, Ruud H., van den Brekel, Michiel W. M., Vens, Conchita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966332/ https://www.ncbi.nlm.nih.gov/pubmed/31998639 http://dx.doi.org/10.3389/fonc.2019.01470 |
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