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JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression
Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling mediates almost all immune regulatory processes, including those that are involved in tumor cell recognition and tumor-driven immune escape. Antitumor immune responses are largely driven by STAT1 and STAT2 induction o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966445/ https://www.ncbi.nlm.nih.gov/pubmed/31842362 http://dx.doi.org/10.3390/cancers11122002 |