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JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression

Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling mediates almost all immune regulatory processes, including those that are involved in tumor cell recognition and tumor-driven immune escape. Antitumor immune responses are largely driven by STAT1 and STAT2 induction o...

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Detalles Bibliográficos
Autores principales: Owen, Katie L., Brockwell, Natasha K., Parker, Belinda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966445/
https://www.ncbi.nlm.nih.gov/pubmed/31842362
http://dx.doi.org/10.3390/cancers11122002