ROCK2 Confers Acquired Gemcitabine Resistance in Pancreatic Cancer Cells by Upregulating Transcription Factor ZEB1

Resistance to chemotherapy is a major clinical challenge in the treatment of pancreatic ductal adenocarcinoma (PDAC). Here, we provide evidence that Rho associated coiled-coil containing protein kinase 2 (ROCK2) maintains gemcitabine resistance in gemcitabine resistant pancreatic cancer cells (GR ce...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Zhou, Yunjiang, Wang, Keke, Li, Tao, Zhang, Minda, Yang, Yunjia, Wang, Rui, Hu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966455/
https://www.ncbi.nlm.nih.gov/pubmed/31783584
http://dx.doi.org/10.3390/cancers11121881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966455/
https://www.ncbi.nlm.nih.gov/pubmed/31783584
http://dx.doi.org/10.3390/cancers11121881

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