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ROCK2 Confers Acquired Gemcitabine Resistance in Pancreatic Cancer Cells by Upregulating Transcription Factor ZEB1

Resistance to chemotherapy is a major clinical challenge in the treatment of pancreatic ductal adenocarcinoma (PDAC). Here, we provide evidence that Rho associated coiled-coil containing protein kinase 2 (ROCK2) maintains gemcitabine resistance in gemcitabine resistant pancreatic cancer cells (GR ce...

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Detalles Bibliográficos
Autores principales:	Zhou, Yang, Zhou, Yunjiang, Wang, Keke, Li, Tao, Zhang, Minda, Yang, Yunjia, Wang, Rui, Hu, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966455/ https://www.ncbi.nlm.nih.gov/pubmed/31783584 http://dx.doi.org/10.3390/cancers11121881

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