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NGF-Enhanced Vasculogenic Properties of Epithelial Ovarian Cancer Cells Is Reduced by Inhibition of the COX-2/PGE(2) Signaling Axis

Epithelial ovarian cancer (EOC) is a lethal gynecological neoplasia characterized by extensive angiogenesis and overexpression of nerve growth factor (NGF). Here, we investigated the mechanism by which NGF increases vascular endothelial growth factor (VEGF) expression and the vasculogenic potential...

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Detalles Bibliográficos
Autores principales: Garrido, Maritza P., Hurtado, Iván, Valenzuela-Valderrama, Manuel, Salvatierra, Renato, Hernández, Andrea, Vega, Margarita, Selman, Alberto, Quest, Andrew F. G., Romero, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966471/
https://www.ncbi.nlm.nih.gov/pubmed/31817839
http://dx.doi.org/10.3390/cancers11121970