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NGF-Enhanced Vasculogenic Properties of Epithelial Ovarian Cancer Cells Is Reduced by Inhibition of the COX-2/PGE(2) Signaling Axis
Epithelial ovarian cancer (EOC) is a lethal gynecological neoplasia characterized by extensive angiogenesis and overexpression of nerve growth factor (NGF). Here, we investigated the mechanism by which NGF increases vascular endothelial growth factor (VEGF) expression and the vasculogenic potential...
Autores principales: | Garrido, Maritza P., Hurtado, Iván, Valenzuela-Valderrama, Manuel, Salvatierra, Renato, Hernández, Andrea, Vega, Margarita, Selman, Alberto, Quest, Andrew F. G., Romero, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966471/ https://www.ncbi.nlm.nih.gov/pubmed/31817839 http://dx.doi.org/10.3390/cancers11121970 |
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