RASSF10 Is a TGFβ-Target That Regulates ASPP2 and E-Cadherin Expression and Acts as Tumor Suppressor That Is Epigenetically Downregulated in Advanced Cancer

The Ras Association Domain Family (RASSF) encodes members of tumor suppressor genes which are frequently inactivated in human cancers. Here, the function and the regulation of RASSF10, that contains a RA (Ras-association) and two coiled domains, was investigated. We utilized mass spectrometry and im...

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Detalles Bibliográficos
Autores principales: Richter, Antje M., Küster, Miriam M., Woods, Michelle L., Walesch, Sara K., Gökyildirim, Mira Y., Krueger, Marcus, Dammann, Reinhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966473/
https://www.ncbi.nlm.nih.gov/pubmed/31817988
http://dx.doi.org/10.3390/cancers11121976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966473/
https://www.ncbi.nlm.nih.gov/pubmed/31817988
http://dx.doi.org/10.3390/cancers11121976

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