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RASSF10 Is a TGFβ-Target That Regulates ASPP2 and E-Cadherin Expression and Acts as Tumor Suppressor That Is Epigenetically Downregulated in Advanced Cancer
The Ras Association Domain Family (RASSF) encodes members of tumor suppressor genes which are frequently inactivated in human cancers. Here, the function and the regulation of RASSF10, that contains a RA (Ras-association) and two coiled domains, was investigated. We utilized mass spectrometry and im...
Autores principales: | Richter, Antje M., Küster, Miriam M., Woods, Michelle L., Walesch, Sara K., Gökyildirim, Mira Y., Krueger, Marcus, Dammann, Reinhard H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966473/ https://www.ncbi.nlm.nih.gov/pubmed/31817988 http://dx.doi.org/10.3390/cancers11121976 |
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