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Role of the YAP-1 Transcriptional Target cIAP2 in the Differential Susceptibility to Chemotherapy of Non-Small-Cell Lung Cancer (NSCLC) Patients with Tumor RASSF1A Gene Methylation from the Phase 3 IFCT-0002 Trial

RASSF1 gene methylation predicts longer disease-free survival (DFS) and overall survival (OS) in patients with early-stage non-small-cell lung cancer treated using paclitaxel-based neo-adjuvant chemotherapy compared to patients receiving a gemcitabine-based regimen, according to the randomized Phase...

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Detalles Bibliográficos
Autores principales: Dubois, Fatéméh, Keller, Maureen, Hoflack, Julien, Maille, Elodie, Antoine, Martine, Westeel, Virginie, Bergot, Emmanuel, Quoix, Elisabeth, Lavolé, Armelle, Bigay-Game, Laurence, Pujol, Jean-Louis, Langlais, Alexandra, Morin, Franck, Zalcman, Gérard, Levallet, Guénaëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966477/
https://www.ncbi.nlm.nih.gov/pubmed/31766357
http://dx.doi.org/10.3390/cancers11121835