Proteogenomics of Colorectal Cancer Liver Metastases: Complementing Precision Oncology with Phenotypic Data

Hotspot testing for activating KRAS mutations is used in precision oncology to select colorectal cancer (CRC) patients who are eligible for anti-EGFR treatment. However, even for KRAS(wildtype) tumors anti-EGFR response rates are <30%, while mutated-KRAS does not entirely rule out response, indic...

Descripción completa

Detalles Bibliográficos
Autores principales: Blank-Landeshammer, Bernhard, Richard, Vincent R., Mitsa, Georgia, Marques, Maud, LeBlanc, André, Kollipara, Laxmikanth, Feldmann, Ingo, Couetoux du Tertre, Mathilde, Gambaro, Karen, McNamara, Suzan, Spatz, Alan, Zahedi, René P., Sickmann, Albert, Batist, Gerald, Borchers, Christoph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966481/
https://www.ncbi.nlm.nih.gov/pubmed/31805664
http://dx.doi.org/10.3390/cancers11121907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966481/
https://www.ncbi.nlm.nih.gov/pubmed/31805664
http://dx.doi.org/10.3390/cancers11121907

Ejemplares similares