Vienna LiverTox Workspace—A Set of Machine Learning Models for Prediction of Interactions Profiles of Small Molecules With Transporters Relevant for Regulatory Agencies

Transporters expressed in the liver play a major role in drug pharmacokinetics and are a key component of the physiological bile flow. Inhibition of these transporters may lead to drug-drug interactions or even drug-induced liver injury. Therefore, predicting the interaction profile of small molecul...

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Detalles Bibliográficos
Autores principales: Montanari, Floriane, Knasmüller, Bernhard, Kohlbacher, Stefan, Hillisch, Christoph, Baierová, Christine, Grandits, Melanie, Ecker, Gerhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966498/
https://www.ncbi.nlm.nih.gov/pubmed/31998690
http://dx.doi.org/10.3389/fchem.2019.00899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966498/
https://www.ncbi.nlm.nih.gov/pubmed/31998690
http://dx.doi.org/10.3389/fchem.2019.00899

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