Hispidulin Enhances TRAIL-Mediated Apoptosis via CaMKKβ/AMPK/USP51 Axis-Mediated Bim Stabilization

Hispidulin, a natural compound present in herbs, has anti-cancer effects. Here, we investigated whether hispidulin sensitizes human carcinoma cells to apoptosis induced by TRAIL. Sub-lethal dosages of TRAIL alone and hispidulin alone does not increase apoptosis, but hispidulin increases sensitivity...

Descripción completa

Detalles Bibliográficos
Autores principales: Woo, Seon Min, Seo, Seung Un, Kim, Sang Hyun, Nam, Ju-Ock, Kim, Shin, Park, Jong-Wook, Min, Kyoung-jin, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966507/
https://www.ncbi.nlm.nih.gov/pubmed/31817696
http://dx.doi.org/10.3390/cancers11121960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966507/
https://www.ncbi.nlm.nih.gov/pubmed/31817696
http://dx.doi.org/10.3390/cancers11121960

Ejemplares similares