The Emerging Role of ESR1 Mutations in Luminal Breast Cancer as a Prognostic and Predictive Biomarker of Response to Endocrine Therapy

Mutations in the hotspot ligand-binding domain of the estrogen receptor (ER) gene ESR1 have recently been recognized as mechanisms of endocrine resistance in endocrine receptor-positive metastatic breast cancer (MBC). Accumulating data suggest these mutations develop under the selective pressure of...

Descripción completa

Detalles Bibliográficos
Autores principales: De Santo, Irene, McCartney, Amelia, Migliaccio, Ilenia, Di Leo, Angelo, Malorni, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966519/
https://www.ncbi.nlm.nih.gov/pubmed/31795152
http://dx.doi.org/10.3390/cancers11121894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966519/
https://www.ncbi.nlm.nih.gov/pubmed/31795152
http://dx.doi.org/10.3390/cancers11121894

Ejemplares similares