p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms

The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair, apoptosis, and senescence. However, according to an increasing number of studies, the p53-mediated canonical DNA damage response is dispensable for tumor suppression. p53 is involved in mechanisms r...

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Detalles Bibliográficos
Autores principales: Pitolli, Consuelo, Wang, Ying, Candi, Eleonora, Shi, Yufang, Melino, Gerry, Amelio, Ivano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966539/
https://www.ncbi.nlm.nih.gov/pubmed/31835405
http://dx.doi.org/10.3390/cancers11121983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966539/
https://www.ncbi.nlm.nih.gov/pubmed/31835405
http://dx.doi.org/10.3390/cancers11121983

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