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The Transfer of Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma

Multiple myeloma (MM) is well-known for the development of drug resistance, leading to relapse. Therefore, finding novel treatment strategies remains necessary. By performing a lipidomics assay on MM patient plasma, we aimed to identify new targets. We observed a dysregulation in the sphingolipid me...

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Detalles Bibliográficos
Autores principales: Faict, Sylvia, Oudaert, Inge, D’Auria, Ludovic, Dehairs, Jonas, Maes, Ken, Vlummens, Philip, De Veirman, Kim, De Bruyne, Elke, Fostier, Karel, Vande Broek, Isabelle, Schots, Rik, Vanderkerken, Karin, Swinnen, Johannes V., Menu, Eline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966559/
https://www.ncbi.nlm.nih.gov/pubmed/31756922
http://dx.doi.org/10.3390/cancers11121823