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Cyst Reduction in a Polycystic Kidney Disease Drosophila Model Using Smac Mimics

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited malady affecting 12.5 million people worldwide. Therapeutic options to treat PKD are limited, due in part to lack of precise knowledge of underlying pathological mechanisms. Mimics of the second mitochondria-derived activator of ca...

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Detalles Bibliográficos
Autores principales: Millet-Boureima, Cassandra, Chingle, Ramesh, Lubell, William D., Gamberi, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966561/
https://www.ncbi.nlm.nih.gov/pubmed/31635379
http://dx.doi.org/10.3390/biomedicines7040082