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Direct Targeting Options for STAT3 and STAT5 in Cancer

Signal transducer and activator of transcription (STAT)3 and STAT5 are important transcription factors that are able to mediate or even drive cancer progression through hyperactivation or gain-of-function mutations. Mutated STAT3 is mainly associated with large granular lymphocytic T-cell leukemia,...

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Detalles Bibliográficos
Autores principales: Orlova, Anna, Wagner, Christina, de Araujo, Elvin D., Bajusz, Dávid, Neubauer, Heidi A., Herling, Marco, Gunning, Patrick T., Keserű, György M., Moriggl, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966570/
https://www.ncbi.nlm.nih.gov/pubmed/31817042
http://dx.doi.org/10.3390/cancers11121930