Exosomal Thrombospondin-1 Disrupts the Integrity of Endothelial Intercellular Junctions to Facilitate Breast Cancer Cell Metastasis

Transendothelial migration of malignant cells plays an essential role in tumor progression and metastasis. The present study revealed that treating human umbilical vein endothelial cells (HUVECs) with exosomes derived from metastatic breast cancer cells increased the number of cancer cells migrating...

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Detalles Bibliográficos
Autores principales: Cen, Junyu, Feng, Lingyun, Ke, Huichuan, Bao, Lifeng, Li, Lin Z., Tanaka, Yoshimasa, Weng, Jun, Su, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966578/
https://www.ncbi.nlm.nih.gov/pubmed/31817450
http://dx.doi.org/10.3390/cancers11121946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966578/
https://www.ncbi.nlm.nih.gov/pubmed/31817450
http://dx.doi.org/10.3390/cancers11121946

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