Cargando…

Exosomal Thrombospondin-1 Disrupts the Integrity of Endothelial Intercellular Junctions to Facilitate Breast Cancer Cell Metastasis

Transendothelial migration of malignant cells plays an essential role in tumor progression and metastasis. The present study revealed that treating human umbilical vein endothelial cells (HUVECs) with exosomes derived from metastatic breast cancer cells increased the number of cancer cells migrating...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cen, Junyu, Feng, Lingyun, Ke, Huichuan, Bao, Lifeng, Li, Lin Z., Tanaka, Yoshimasa, Weng, Jun, Su, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966578/ https://www.ncbi.nlm.nih.gov/pubmed/31817450 http://dx.doi.org/10.3390/cancers11121946

Ejemplares similares

Cell chirality regulates intercellular junctions and endothelial permeability
por: Fan, Jie, et al.
Publicado: (2018)

Tumor Necrosis Factor-Alpha Disrupts Cx43-Mediated Corneal Endothelial Gap Junction Intercellular Communication
por: Meng, Jufeng, et al.
Publicado: (2022)

Treponema pallidum Disrupts VE-Cadherin Intercellular Junctions and Traverses Endothelial Barriers Using a Cholesterol-Dependent Mechanism
por: Lithgow, Karen V., et al.
Publicado: (2021)

The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner
por: Tarafdar, Anuradha, et al.
Publicado: (2022)

Dexamethasone disrupts intercellular junction formation and cytoskeleton organization in human trabecular meshwork cells
por: Zhuo, Ye Hong, et al.
Publicado: (2010)

Intercellular junctions and transfer of small molecules in primary vascular endothelial cultures
Publicado: (1982)

Exosomes for Intramyocardial Intercellular Communication
por: Cervio, Elisabetta, et al.
Publicado: (2015)

Exosomes as Intercellular Messengers in Hypertension
por: Arishe, Olufunke Omolola, et al.
Publicado: (2021)

p120 catenin associates with kinesin and facilitates the transport of cadherin–catenin complexes to intercellular junctions
por: Chen, Xinyu, et al.
Publicado: (2003)

Exosomes: secreted vesicles and intercellular communications
por: Théry, Clotilde
Publicado: (2011)

Thrombospondin modulates focal adhesions in endothelial cells
Publicado: (1989)

A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions
Publicado: (1989)

High-Glucose-Induced Rab20 Upregulation Disrupts Gap Junction Intercellular Communication and Promotes Apoptosis in Retinal Endothelial and Müller Cells: Implications for Diabetic Retinopathy
por: Kim, Dongjoon, et al.
Publicado: (2020)

The Regulation of the Hippo Pathway by Intercellular Junction Proteins
por: Ahmad, Usama Sharif, et al.
Publicado: (2022)

The Beneficial Effect of HES on Vascular Permeability and Its Relationship With Endothelial Glycocalyx and Intercellular Junction After Hemorrhagic Shock
por: Zhao, Hongliang, et al.
Publicado: (2020)

Exosomes Are Unlikely Involved in Intercellular Nef Transfer
por: Luo, Xiaoyu, et al.
Publicado: (2015)

Vehicles of intercellular communication: exosomes and HIV-1
por: Welch, Jennifer L., et al.
Publicado: (2019)

Synthesis and secretion of thrombospondin by cultured human endothelial cells
Publicado: (1982)

Salt bridges gate α-catenin activation at intercellular junctions
por: Barrick, Samantha, et al.
Publicado: (2018)

Role of thrombospondin-1 and thrombospondin-2 in cardiovascular diseases (Review)
por: Zhang, Kaijie, et al.
Publicado: (2020)

Thrombospondin-4 controls matrix assembly during development and repair of myotendinous junctions
por: Subramanian, Arul, et al.
Publicado: (2014)

Cancer-associated fibroblasts facilitate breast cancer progression through exosomal circTBPL1-mediated intercellular communication
por: Ye, Fangzhou, et al.
Publicado: (2023)

Desmosomes: Essential contributors to an integrated intercellular junction network
por: Green, Kathleen J, et al.
Publicado: (2019)

Local Oxidative Stress Expansion through Endothelial Cells – A Key Role for Gap Junction Intercellular Communication
por: Feine, Ilan, et al.
Publicado: (2012)

Influence of vascular endothelial growth factor and radiation on gap junctional intercellular communication in glioblastoma multiforme cell lines
por: Krcek, Reinhardt, et al.
Publicado: (2017)

Effects of heat shock on the expression of thrombospondin by endothelial cells in culture
Publicado: (1988)

Interactions of thrombospondin with endothelial cells: receptor- mediated binding and degradation
Publicado: (1987)

Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders
por: Schneider, Anja, et al.
Publicado: (2012)

Intercellular Communication by Exosome-Derived microRNAs in Cancer
por: Hannafon, Bethany N., et al.
Publicado: (2013)

Exosomes Mediate the Intercellular Communication after Myocardial Infarction
por: Yuan, Ming-Jie, et al.
Publicado: (2016)

Intercellular transmission of Seneca Valley virus mediated by exosomes
por: Xu, Guowei, et al.
Publicado: (2020)

Exosomes: Emerging Players of Intercellular Communication in Tumor Microenvironment
por: Maheshwari, Shrankhla, et al.
Publicado: (2014)

Small but Mighty—Exosomes, Novel Intercellular Messengers in Neurodegeneration
por: Kumari, Meena, et al.
Publicado: (2022)

Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration
por: Chan, Lai Yue, et al.
Publicado: (2015)

Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions
por: Qiu, Yongzhi, et al.
Publicado: (2017)

Penton-Dodecahedral Particles Trigger Opening of Intercellular Junctions and Facilitate Viral Spread during Adenovirus Serotype 3 Infection of Epithelial Cells
por: Lu, Zhuo-Zhuang, et al.
Publicado: (2013)

The biogenesis and secretion of exosomes and multivesicular bodies (MVBs): Intercellular shuttles and implications in human diseases
por: Xu, Minxue, et al.
Publicado: (2022)

Exosomes facilitate intercellular communication between uterine perivascular adipose tissue and vascular smooth muscle cells in pregnant rats
por: Osikoya, Oluwatobiloba, et al.
Publicado: (2022)

Intercellular calcium signaling via gap junctions in glioma cells
Publicado: (1992)

HEXAGONAL ARRAY OF SUBUNITS IN INTERCELLULAR JUNCTIONS OF THE MOUSE HEART AND LIVER
por: Revel, J. P., et al.
Publicado: (1967)

Cannot write session to /tmp/vufind_sessions/sess_g0psbv02kcvjvvujv5epigppnq