Cargando…

Somatic Mutation of PIK3CA (H1047R) Is a Common Driver Mutation Hotspot in Canine Mammary Tumors as Well as Human Breast Cancers

Breast cancer is one of the most frequently diagnosed cancers in both women and female dogs. Genome-wide association studies in human breast cancer (HBC) have identified hundreds of genetic variations and somatic driver mutations. However, only a handful of variants have been studied for rare HBC an...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Kang-Hoon, Hwang, Hyeon-Ji, Noh, Hyun Ji, Shin, Tae-Jin, Cho, Je-Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966585/
https://www.ncbi.nlm.nih.gov/pubmed/31842489
http://dx.doi.org/10.3390/cancers11122006