Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy

Oncogene-induced STAT3-activation is central to tumor progression by promoting cancer cell expression of pro-angiogenic and immunosuppressive factors. STAT3 is also activated in infiltrating immune cells including tumor-associated macrophages (TAM) amplifying immune suppression. Consequently, STAT3...

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Detalles Bibliográficos
Autores principales: Verdeil, Grégory, Lawrence, Toby, Schmitt-Verhulst, Anne-Marie, Auphan-Anezin, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966642/
https://www.ncbi.nlm.nih.gov/pubmed/31766350
http://dx.doi.org/10.3390/cancers11121832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966642/
https://www.ncbi.nlm.nih.gov/pubmed/31766350
http://dx.doi.org/10.3390/cancers11121832

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