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Exploiting Current Understanding of Hypoxia Mediated Tumour Progression for Nanotherapeutic Development
Hypoxia is one of the most common phenotypes of malignant tumours. Hypoxia leads to the increased activity of hypoxia-inducible factors (HIFs), which regulate the expression of genes controlling a raft of pro-tumour phenotypes. These include maintenance of the cancer stem cell compartment, epithelia...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966647/ https://www.ncbi.nlm.nih.gov/pubmed/31835751 http://dx.doi.org/10.3390/cancers11121989 |