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Exploiting Current Understanding of Hypoxia Mediated Tumour Progression for Nanotherapeutic Development

Hypoxia is one of the most common phenotypes of malignant tumours. Hypoxia leads to the increased activity of hypoxia-inducible factors (HIFs), which regulate the expression of genes controlling a raft of pro-tumour phenotypes. These include maintenance of the cancer stem cell compartment, epithelia...

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Detalles Bibliográficos
Autores principales: Feng, Jie, Byrne, Niall M., Al Jamal, Wafa, Coulter, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966647/
https://www.ncbi.nlm.nih.gov/pubmed/31835751
http://dx.doi.org/10.3390/cancers11121989