Cargando…
Exploiting Current Understanding of Hypoxia Mediated Tumour Progression for Nanotherapeutic Development
Hypoxia is one of the most common phenotypes of malignant tumours. Hypoxia leads to the increased activity of hypoxia-inducible factors (HIFs), which regulate the expression of genes controlling a raft of pro-tumour phenotypes. These include maintenance of the cancer stem cell compartment, epithelia...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966647/ https://www.ncbi.nlm.nih.gov/pubmed/31835751 http://dx.doi.org/10.3390/cancers11121989 |