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ACLY (ATP Citrate Lyase) Mediates Radioresistance in Head and Neck Squamous Cell Carcinomas and is a Novel Predictive Radiotherapy Biomarker

Radiotherapy is an important treatment modality of head and neck squamous cell carcinomas (HNSCC). Multiple links have been described between the metabolic activity of tumors and their clinical outcome. Here we test the hypothesis that metabolic features determine radiosensitivity, explaining the re...

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Detalles Bibliográficos
Autores principales: Göttgens, Eva-Leonne, van den Heuvel, Corina NAM, de Jong, Monique C, Kaanders, Johannes HAM, Leenders, William PJ, Ansems, Marleen, Bussink, Johan, Span, Paul N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966650/
https://www.ncbi.nlm.nih.gov/pubmed/31817870
http://dx.doi.org/10.3390/cancers11121971