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ACLY (ATP Citrate Lyase) Mediates Radioresistance in Head and Neck Squamous Cell Carcinomas and is a Novel Predictive Radiotherapy Biomarker
Radiotherapy is an important treatment modality of head and neck squamous cell carcinomas (HNSCC). Multiple links have been described between the metabolic activity of tumors and their clinical outcome. Here we test the hypothesis that metabolic features determine radiosensitivity, explaining the re...
Autores principales: | Göttgens, Eva-Leonne, van den Heuvel, Corina NAM, de Jong, Monique C, Kaanders, Johannes HAM, Leenders, William PJ, Ansems, Marleen, Bussink, Johan, Span, Paul N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966650/ https://www.ncbi.nlm.nih.gov/pubmed/31817870 http://dx.doi.org/10.3390/cancers11121971 |
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