Double-Edged Lipid Nanoparticles Combining Liposome-Bound TRAIL and Encapsulated Doxorubicin Showing an Extraordinary Synergistic Pro-Apoptotic Potential

Although TRAIL (TNF-related apoptosis-inducing ligand, also known as Apo2L) was described as capable of inducing apoptosis in transformed cells while sparing normal cells, limited results obtained in clinical trials has limited its use as an anti-tumor agent. Consequently, novel TRAIL formulations w...

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Detalles Bibliográficos
Autores principales: De Miguel, Diego, Gallego-Lleyda, Ana, Martinez-Ara, Miguel, Plou, Javier, Anel, Alberto, Martinez-Lostao, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966652/
https://www.ncbi.nlm.nih.gov/pubmed/31817469
http://dx.doi.org/10.3390/cancers11121948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966652/
https://www.ncbi.nlm.nih.gov/pubmed/31817469
http://dx.doi.org/10.3390/cancers11121948

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