Simultaneous Multi-Organ Metastases from Chemo-Resistant Triple-Negative Breast Cancer Are Prevented by Interfering with WNT-Signaling

Triple-negative breast cancers (TNBCs), which lack specific targeted therapy options, evolve into highly chemo-resistant tumors that metastasize to multiple organs simultaneously. We have previously shown that TNBCs maintain an activated WNT10B-driven network that drives metastasis. Pharmacologic in...

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Detalles Bibliográficos
Autores principales: Fatima, Iram, El-Ayachi, Ikbale, Playa, Hilaire C., Alva-Ornelas, Jackelyn A., Khalid, Aysha B., Kuenzinger, William L., Wend, Peter, Pence, Jackelyn C., Brakefield, Lauren, Krutilina, Raisa I., Johnson, Daniel L., O’Regan, Ruth M., Seewaldt, Victoria, Seagroves, Tiffany N., Krum, Susan A., Miranda-Carboni, Gustavo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966654/
https://www.ncbi.nlm.nih.gov/pubmed/31861131
http://dx.doi.org/10.3390/cancers11122039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966654/
https://www.ncbi.nlm.nih.gov/pubmed/31861131
http://dx.doi.org/10.3390/cancers11122039

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