Changes of O(6)-Methylguanine DNA Methyltransferase (MGMT) Promoter Methylation in Glioblastoma Relapse—A Meta-Analysis Type Literature Review

Methylation of the O(6)-methylguanine DNA methyltransferase (MGMT) promoter has emerged as strong prognostic factor in the therapy of glioblastoma multiforme. It is associated with an improved response to chemotherapy with temozolomide and longer overall survival. MGMT promoter methylation has impli...

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Detalles Bibliográficos
Autores principales: Feldheim, Jonas, Kessler, Almuth F., Monoranu, Camelia M., Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966671/
https://www.ncbi.nlm.nih.gov/pubmed/31766430
http://dx.doi.org/10.3390/cancers11121837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966671/
https://www.ncbi.nlm.nih.gov/pubmed/31766430
http://dx.doi.org/10.3390/cancers11121837

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