Efficacy and Adverse Events in Metastatic Melanoma Patients Treated with Combination BRAF Plus MEK Inhibitors Versus BRAF Inhibitors: A Systematic Review

We reviewed the literature to assess the efficacy and risk of constitutional, cardiac, gastrointestinal, and dermatological toxicities of combined BRAF plus MEK inhibitors versus BRAF inhibitors alone in patients with metastatic melanoma with BRAF mutations. Searches were conducted in PubMed, Cochra...

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Detalles Bibliográficos
Autores principales: Greco, Austin, Safi, Danish, Swami, Umang, Ginader, Tim, Milhem, Mohammed, Zakharia, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966686/
https://www.ncbi.nlm.nih.gov/pubmed/31817473
http://dx.doi.org/10.3390/cancers11121950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966686/
https://www.ncbi.nlm.nih.gov/pubmed/31817473
http://dx.doi.org/10.3390/cancers11121950

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