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Efficacy and Adverse Events in Metastatic Melanoma Patients Treated with Combination BRAF Plus MEK Inhibitors Versus BRAF Inhibitors: A Systematic Review
We reviewed the literature to assess the efficacy and risk of constitutional, cardiac, gastrointestinal, and dermatological toxicities of combined BRAF plus MEK inhibitors versus BRAF inhibitors alone in patients with metastatic melanoma with BRAF mutations. Searches were conducted in PubMed, Cochra...
Autores principales: | Greco, Austin, Safi, Danish, Swami, Umang, Ginader, Tim, Milhem, Mohammed, Zakharia, Yousef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966686/ https://www.ncbi.nlm.nih.gov/pubmed/31817473 http://dx.doi.org/10.3390/cancers11121950 |
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