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Gigantol Targets Cancer Stem Cells and Destabilizes Tumors via the Suppression of the PI3K/AKT and JAK/STAT Pathways in Ectopic Lung Cancer Xenografts

Lung cancer has long been recognized as an important world heath concern due to its high incidence and death rate. The failure of treatment strategies, as well as the regrowth of the disease driven by cancer stem cells (CSCs) residing in the tumor, lead to the urgent need for a novel CSC-targeting t...

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Detalles Bibliográficos
Autores principales: Losuwannarak, Nattanan, Maiuthed, Arnatchai, Kitkumthorn, Nakarin, Leelahavanichkul, Asada, Roytrakul, Sittiruk, Chanvorachote, Pithi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966687/
https://www.ncbi.nlm.nih.gov/pubmed/31861050
http://dx.doi.org/10.3390/cancers11122032