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cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel

BACKGROUND: Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but our understanding of how the effects of genetic variants...

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Detalles Bibliográficos
Autores principales: Frochaux, Michael V., Bou Sleiman, Maroun, Gardeux, Vincent, Dainese, Riccardo, Hollis, Brian, Litovchenko, Maria, Braman, Virginie S., Andreani, Tommaso, Osman, Dani, Deplancke, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966807/
https://www.ncbi.nlm.nih.gov/pubmed/31948474
http://dx.doi.org/10.1186/s13059-019-1912-z