The PI3K subunits, P110α and P110β are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer

BACKGROUND: PI3K/AKT is a vital signaling pathway in humans. Recently, several PI3K/AKT inhibitors were reported to have the ability to reverse cancer multidrug resistance (MDR); however, specific targets in the PI3K/AKT pathways and the mechanisms associated with MDR have not been found because man...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Lei, Li, Yidong, Wang, Qianchao, Chen, Zhuo, Li, Xiaoyun, Wu, Zhuoxun, Hu, Chaohua, Liao, Dan, Zhang, Wei, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966863/
https://www.ncbi.nlm.nih.gov/pubmed/31952518
http://dx.doi.org/10.1186/s12943-019-1112-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966863/
https://www.ncbi.nlm.nih.gov/pubmed/31952518
http://dx.doi.org/10.1186/s12943-019-1112-1

Ejemplares similares