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CHROMATIX: computing the functional landscape of many-body chromatin interactions in transcriptionally active loci from deconvolved single cells

Chromatin interactions are important for gene regulation and cellular specialization. Emerging evidence suggests many-body spatial interactions play important roles in condensing super-enhancer regions into a cohesive transcriptional apparatus. Chromosome conformation studies using Hi-C are limited...

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Detalles Bibliográficos
Autores principales: Perez-Rathke, Alan, Sun, Qiu, Wang, Boshen, Boeva, Valentina, Shao, Zhifeng, Liang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966897/
https://www.ncbi.nlm.nih.gov/pubmed/31948478
http://dx.doi.org/10.1186/s13059-019-1904-z