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CHROMATIX: computing the functional landscape of many-body chromatin interactions in transcriptionally active loci from deconvolved single cells
Chromatin interactions are important for gene regulation and cellular specialization. Emerging evidence suggests many-body spatial interactions play important roles in condensing super-enhancer regions into a cohesive transcriptional apparatus. Chromosome conformation studies using Hi-C are limited...
Autores principales: | Perez-Rathke, Alan, Sun, Qiu, Wang, Boshen, Boeva, Valentina, Shao, Zhifeng, Liang, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966897/ https://www.ncbi.nlm.nih.gov/pubmed/31948478 http://dx.doi.org/10.1186/s13059-019-1904-z |
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