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Tizanidine (Hydrochloride) Inhibits A549 Lung Cancer Cell Proliferation and Motility Through Regulating Nischarin

PURPOSE: Tizanidine hydrochloride (TZN) is a centrally acting α(2)-adrenergic agonist. In this study, we aimed to explore the role of TZN on human lung cancer and to elucidate its underlying mechanisms. METHODS: The effect of TZN treatment in A549 cell proliferation, migration, invasion and apoptosi...

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Detalles Bibliográficos
Autores principales: Zhao, Liang, Zhao, Gefei, Xue, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966956/
https://www.ncbi.nlm.nih.gov/pubmed/32021275
http://dx.doi.org/10.2147/OTT.S228317