Tuning of NK-Specific HLA-C Expression by Alternative mRNA Splicing

A complex system regulating HLA-C expression in NK cells, driven by an NK-specific promoter that produces alternatively spliced variants of the 5′-UTR has been recently identified. Exon content of the NK-specific 5′-UTR varies strikingly across HLA-C alleles, with some exons being allele specific. I...

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Detalles Bibliográficos
Autores principales: Goodson-Gregg, Frederick J., Rothbard, Brian, Zhang, Amy, Wright, Paul W., Li, Hongchuan, Walker-Sperling, Victoria E., Carrington, Mary, Anderson, Stephen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966967/
https://www.ncbi.nlm.nih.gov/pubmed/31998314
http://dx.doi.org/10.3389/fimmu.2019.03034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966967/
https://www.ncbi.nlm.nih.gov/pubmed/31998314
http://dx.doi.org/10.3389/fimmu.2019.03034

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