Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling

BACKGROUND: Our previous study showed Musashi2 (MSI2) promoted chemotherapy resistance and pernicious biology of pancreatic cancer (PC) by down-regulating Numb and p53. We further explored the novel molecular mechanism involving its oncogenic role in PC development. METHODS: We investigated the pote...

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Detalles Bibliográficos
Autores principales: Sheng, Weiwei, Shi, Xiaoyang, Lin, Yiheng, Tang, Jingtong, Jia, Chao, Cao, Rongxian, Sun, Jian, Wang, Guosen, Zhou, Lei, Dong, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6967093/
https://www.ncbi.nlm.nih.gov/pubmed/31952541
http://dx.doi.org/10.1186/s13046-020-1521-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6967093/
https://www.ncbi.nlm.nih.gov/pubmed/31952541
http://dx.doi.org/10.1186/s13046-020-1521-4

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